| 单词 | glycosylation |
| 释义 | glycosylation, n. Biochem.|glaɪkɒsɪˈleɪʃən|
[f. *glycosyl n. + -ation.]
The introduction of a glycosyl group into a molecule or compound, esp. a protein, by the formation of a glycosidic bond.
1945Jrnl. Amer. Chem. Soc. LXVII. 1763/2 The glycosylation of benzene with fully acetylated sugars has been shown to proceed in the presence of aluminium chloride. 1979Sci. Amer. Jan. 43/3 To study the insertion and glycosylation of the protein, membranes from the endoplasmic reticulum that have been stripped of their endogenous ribosomes must also be present. 1987Oxf. Textbk. Med. (ed. 2) I. viii. 24 It has been suggested that vitamin A plays a role in the glycosylation of glycoproteins.
So glyˈcosylate v. trans., to add a glycosyl group into (a molecule or compound); glyˈcosylated ppl. a.
1945Jrnl. Amer. Chem. Soc. LXVII. 1975/1 The stereochemical configurations in all the glycosylated aromatic hydrocarbons prepared in the previous catalytic studies must, therefore, parallel the configurations of the parent sugars. Ibid. 1975/2 It is interesting briefly to contrast the Grignard and Friedel–Crafts methods for glycosylating hydrocarbons. 1979Sci. Amer. Nov. 59/2 In the blood of diabetics glycosylated forms of hemoglobin are unusually common. |
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