英语词汇“pyrimethamine”的英英意思、用法、释义、翻译、读音、例句、短语、词组、英语词典-本地帮

单词

pyrimethamine

释义

pyrimethamine Pharm.|pɪrɪˈmɛθəmiːn|
[f. pyrimidine + ethyl + amine.]
A white crystalline solid, 2,4-diamino-5-p-chlorophenyl-6-ethylpyrimidine, C₁₂H₁₃N₄Cl₁ which is given orally for the prophylaxis and suppression of malaria.
1953Brit. Med. Jrnl. 31 Jan. 253/1 Pyrimethamine..is the latest of the new synthetic anti-malarial drugs to be tested by us... This compound is produced by Burroughs Wellcome & Co. under the trade name ‘daraprim’.1961New Scientist 20 Apr. 120/1 Pyrimethamine resistance has appeared in some districts in East Africa.1966Lancet 24 Dec. 1382/1 The combination of dapsone to shorten the red-blood-cell life-span and pyrimethamine to inhibit erythropoiesis has now been used successfully on five patients with secondary polycythæmia.1976Ibid. 4 Dec. 1257/1 When a dose of 25 mg weekly is taken for malarial prophylaxis, pyrimethamine is unlikely to produce adverse hæmatological effects except in those actually or potentially folate deficient.

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