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2025-07-20

“pharmacophore”的英英意思

单词 pharmacophore
释义 pharmacophore, n. Pharmacol.
Brit. |ˈfɑːməkəˌfɔː|, U.S. |ˈfɑrməkəˌfɔ(ə)r|
[‹ pharmaco- comb. form + -phore comb. form, after pharmacophoric adj.]
The part of a molecule that is responsible for its characteristic pharmacological activity; a pharmacologically active group.
1964Biochem. Pharmacol. 13 332 The second is a specific structural requirement for which we will use the term ‘pharmacophore’.1971L. B. Kier Molecular Orbital Theory in Drug Res. viii. 170 The molecule is permitted to assume a pattern identical to that previously calculated for the muscarinic pharmacophore.1977Jrnl. Medicinal Chem. 20 85 Attempts to elucidate the prolactin release inhibiting pharmacophore within the ergoline structure.1994Chem. in Brit. Oct. 809/2 Drug design strategy..generates possible pharmacophores based on a set of biologically active compounds.2000Denver Post 10 Sept. l27 (advt.) A dynamic drug discovery company applying the latest innovations..for identification and characterization of pharmacophores from natural products.
“pharmacophore”的英英意思

 

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